Calorie Restriction Weight Loss Avoids High Metabolic Rate, which Equals Death

Go on to Google and search on increasing metabolism weight loss. You’ll get more than six million hits. And just think about it: How many diet plans and weight-loss products claim to help you lose weight by increasing metabolic rate? Even some misguided calorie restriction diet plans recommend increasing metabolic rate.

They forgot to say that you may also lose your life. A new study from The Journal of Clinical Endocrinology & Metabolism confirms what CR Way travelers already intuitively know: A higher resting metabolic rate is associated with early mortality. In fact, for each 100-kilocalorie (the calories that we count) increase in energy expenditure per 24 hours, the likelihood of natural mortality increased by 1.29 percent.

Higher energy expenditure in humans predicts natural mortality.

Journal of Clinical Endocrinology and Metabolism. 2011 Jun;96(6):E972-6. Epub 2011 Mar 30.

Jumpertz R, Hanson RL, Sievers ML, Bennett PH, Nelson RG, Krakoff J.

MD, National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases, Department of Health and Human Services, 4212 North 16th Street, Phoenix, Arizona 85016.

Context: Higher metabolic rates increase free radical formation, which may accelerate aging and lead to early mortality.

Objective: Our objective was to determine whether higher metabolic rates measured by two different methods predict early natural mortality in humans.

Design: Nondiabetic healthy Pima Indian volunteers (n = 652) were admitted to an inpatient unit for approximately 7 days as part of a longitudinal study of obesity and diabetes risk factors. Vital status of study participants was determined through December 31, 2006.

•         Twenty-four-hour energy expenditure (24EE) was measured in 508 individuals,

•         resting metabolic rate (RMR) was measured in 384 individuals,

•         and 240 underwent both measurements on separate days.

Data for 24EE were collected in a respiratory chamber between 1985 and 2006 with a mean follow-up time of 11.1 (standard deviation, 6.5) yr and for RMR using an open-circuit respiratory hood system between 1982 and 2006 with a mean follow-up time of 15.4 (sd, 6.3) yr. Cox regression models were used to test the effect of EE on natural mortality, controlled for age, sex, and body weight.

Results: In both groups, 27 natural deaths occurred during the study period. For each 100-kcal/24 h increase in EE, the risk of natural mortality increased by 1.29 (95% confidence interval = 1.00-1.66; P < 0.05) in the 24EE group and by 1.25 (95% confidence interval = 1.01-1.55; P < 0.05) in the RMR group, after adjustment for age, sex, and body weight in proportional hazard analyses.

Conclusions Higher metabolic rates as reflected by 24EE or RMR predict early natural mortality, indicating that higher energy turnover may accelerate aging in humans.

PMID:21450984 – lightly edited from National Institutes of Health, National Library of Medicine, PubMed access to citations to biomedical literature in MEDLINE.

Meanwhile, the Washington University team did superb work on our CR cohort, showing that T3, an indicator of metabolic rate, is lowered by calorie restriction, as is seen in animal studies.*

*Fontana, L, Klein S, Holloszy J.O., Premachandra B.N. Effect of Long term Calorie Restriction with Adequate Protein and Micronutrients on Thyroid Hormones. Journal of Clinical Endocrinology & Metabolish 2006; 91:3232-3235.


A Healthful Calorie Restriction Diet

So is someone who needs to lose weight doomed to failure by the CR Way’s metabolic rate-lowering lifestyle?

Hardly. The combination of low calorie intake plus low glucose levels forces the body into a fat-burning mode as described in this blog post.

What you are really doing by following a calorie restriction dietwith this lifestyle is allowing your ancient defense system, which was developed when living organisms needed to go for long periods without food – to protect them.

•         Cell signals block fat-forming genes – providing you with energy from fat stores.

•         Pounds melt away not because you are increasing resting metabolic rate, but because fewer calories are available (not less food) in the first place,  and

•         Those that are available, keep glucose levels low – another important characteristic of a healthful weight loss diet.


For more see

The CR Way to Healthful Weight Loss


CR Way to Calorie Restriction, a healthy way to lose weight


What do our members say?

Just want to tell you both that with your help, encouragement, CR Way NutriBase and, most importantly, your example, I almost painlessly shed about one pound per week over the last 23 weeks. I look forward to my upcoming physical!


Most sincerely,

Mike Bell, Kenosha, WI

Would you set your house on fire?

If you had a fire extinguisher in the house, would you set your house on fire if you thought you could put it out?

Ridiculous, isn’t it!

In fact, if you made it a habit, eventually your fire extinguisher might not work and your house would burn down.

Think of the analogy with your own body. We talked with someone the other day who, when we suggested how to prevent arthritis, she said, there are medications for that. Sure, one could live a lifestyle that creates illness and indeed medications might take care of illnesses for a while. But is that not the equivalent of setting your house on fire? At some point, you might not be able to put the fire out.

We have a friend whom we love very much. She followed a dangerous high saturated fat, high GI diet along with smoking for her adult life, until around age 50. Then, all of a sudden, she faced a fire, she almost didn’t put out: a massive heart attack, triple bypass and now less than 20% of her heart muscle is available for use. You would think that she would take steps to put out the fire in her house, and yet, that didn’t happen. Yes, she let the smoking go but maintained the high saturated fat diet that would be likely to make anyone ill – much less a person who has already  had a heart attack. She was setting her house on fire again even when a part of it had burned down. Suddenly, one day she drove into her favorite fast food restaurant’s parking lot and blacked out. – letting her car hit another’s. When she got out of her car to assess the damage, she fell to the ground. Now, lying flat on her back in a nursing home, no one is sure if she will get a third chance to put her fire out.

The CR Way is about keeping your body optimally healthy. Most people find, after following the diet, they don’t even need the medications they thought were so important before. Let us help you keep from starting a fire you can’t put out and welcome you to a better, longer life.Become a Healthy Start Member. The price is good. It’s FREE! And the value is good too: PRICELESS! Nothing is more valuable than having your health.

Meeting at Spindler Lab may lengthen your life

It’s the morning after our meeting at the Spindler Lab in California. We are pumped. What an extraordinary time! We launched the CR-RNA study. It will likely help you determine many aspects of your lifestyle – ultimately helping to guide all of us in planning our CR Way lifestyles to improve health and likely extend lifespan even more.

We had fun photographing some of the highlights of our trip. Here, Meredith and Dr. Stephen Spindler pose for a photo.


Great studies like the one that follows this paragraph convinced us that Drs. Spindler and Dhahbi were the scientists who should look at the cell signaling of long term serious calorie restrictors. We wanted them to identify the cell patterns involved in slowing aging and focus on discovering compounds and lifestyle changes that could facilitate the body’s taking full advantage of living the CR Way.

Identification of Calorie Restriction Mimetic Drugs Using Microarray Profiling

Dhahbi JM, Mote PL, Fahy GM, Spindler SR.

Dept. of Biochemistry, U. California, Riverside, CA 92521, USA.

Physiological Genomics. 2005 Nov 17;23(3):343-50. Epub 2005 Sep 27.

PMID: 16189280

In case you are new to the idea of finding a CR mimetic, scientists have been looking for drugs that would mimic calorie restriction’s extension of life without limiting calories. Indeed, that will likely become possible from some of the discoveries you’ll learn about from the Spindler lab. And while that may be all that some people want from their CR Way lifestyle, there are those of us who love low-calorie living and hope that with the discovery of mimetics more people join the party. After all, it’s easy enough for us to limit calories by 25% or 30%, but that’s usually a cut-off point. It’s not wise for most humans to limit calories more than that because of the risks of decreased bone density and muscle strength caused by very low weight.

So we hope for additional ways to slow aging and, believe us, they are coming. Drs. Spindler and Dhahbi have just finished a multi-year study, identifying substances that will extend lifespan in lab animals. When we came into the office this morning, an email from Dr. Spindler was waiting in our inbox with the results from some of these studies that have been published. Here is one of them, showing that inhibition of certain kinases (Kinases are enzymes in your cells that facilitate energy transfer to activate cellular processes) can extend lifespan.

Novel Protein Kinase Signaling Systems Regulating Lifespan Identified by Small Molecule Library Screening Using Drosophila

Stephen R. Spindler,* Rui Li, Joseph M. Dhahbi, Amy Yamakawa and Frank Sauer

PLoS One. 2012; 7(2): e29782.

PMCID: PMC3 282711


Drs. Spindler and Dhahbi will join upcoming CR Way teleconferences. This is a rare opportunity to hear these scientists discuss their research and ask questions.  Find out more.

Scientists answer your questions at next CR Way teleconference

Sixteen years ago, two visionary scientists, Drs. Stephen Spindler and Joseph Dhahbi began publishing the results of a quest to help people live longer. Focusing on calorie restriction, the only scientifically proven way to extend lifespan, Drs. Spindler and Dhahbi decided to concentrate on identifying cellular regulators that control calorie restriction’s beneficial effects. They looked at how CR changes cell signaling patterns. Their work identified the first calorie restriction mimetic, Metformin, as analyzed in this study.

Identification of potential caloric restriction mimetics by microarray profiling.

Spindler and Dhahbi are poised to provide profound new insights for slowing aging. The results of their four years of studying candidate compounds for extending lifespan are just starting to be reported. We discussed this as part of the CR Way blog: Meeting at Spindler Lab may lengthen your life. Soon longevity activists will learn that some favorite supplements do nothing to change rate of aging (some may accelerate it) while others are likely to extend life.

We are thrilled to announce that Drs. Spindler and Dhahbi have graciously agreed to join us in forthcoming CR Way teleconferences. The first one is set for Wednesday, July 11, at 7:30 PM, ET.

Available to supporting members of, CR Way teleconferences allow time for questions by attendees. Come, hear the scientists discuss their latest work and how it applies to you. If you send your questions in advance, we will submit them to the scientists so they can think about how best to answer you.

To join this historic occasion, become a supporting member of Choose a membership that fits your needs . Use the  e-mail address that’s associated with your membership  to send a note to, requesting the call-in details.  Please be sure to tell us that you want to join the Spindler-Dhahbi teleconference on July 11. This is  just the beginning. We hold live teleconferences twice monthly for supporting members.

Ice Cream Addiction: How the CR Way to calorie restriction can help

I remember him well, how he used to love to sit on the red couch and watch TV after dinner. Tall, handsome, with a dark, thick head of hair – and about 20 pounds overweight. The grey suit he wore to work did a good job of hiding his extra weight.

Before he sat down, he would go to the freezer to get his ice cream fix: Chocolate, vanilla – the freezer usually had a backup carton or two of his favorite flavors. Then there were the exotic flavors of the moment that caught his attention – English toffee, Oreo cookie, watermelon.

It was amazing to watch the ice cream man eat his dinner, before he had his ice cream fix. He was capable of downing some the most delicious meals within the blink of an eye, then leaving the table for the emotional respite from work pressures: ice cream, sometimes with a piece of pie or cake or whatever his wife had fixed for dessert.

The fat and the sugar from the ice cream would make him dozy, so as he progressed into his fifties he would often fall asleep after his ice cream, unless there was a really interesting TV program that caught his attention. By 10 or 11  o’clock he would wake up to listen to the news. Fired up by his0 nap and what he’d hear on the news, he would often have another bowl of ice cream, sending blood to his stomach and making him fall asleep quickly.

Five to six hours later, he would wake up tired. Then a few jolts of coffee was enough to help him get his day started sometimes – wondering why he slept so poorly.

For a few decades, time seemed suspended for the ice cream man. Good genes may have helped him get by with his ice cream habit and seemingly little price to pay. Yet there were unheeded warning signals: less energy, high blood pressure, vision loss – reducing his quality of life, something that many people grow to accept.

Then in his early sixties, the dark side of ice cream addiction began to rear its ugly head. At first, it was manageable. He had a few minor strokes, which produced blurring of vision, a warning of what was to come.

Then the ice cream man had some bad luck: A young driver lost control of her car and hit his car from behind. He saw her car in the rear view and ducked below the seat just in time to avoid serious injury or so it seemed. But the stress and adrenaline from the accident caused him to have a major stroke, causing loss of control of his left leg – for the rest of his life.

From there hell broke lose. Bleeding diverticula in his gut caused him to pass out on the bathroom floor. He was lucky to make it to the hospital in time to save his life, but part of his colon had to be removed. He returned home with strong warnings from doctors to change his diet.

The next time was worse. His limping, unsteady gait somehow caused him to fall down hard on his kitchen floor. This time his stay at the hospital was marked by a heart attack. Several bypasses were necessary to keep his plaque-clogged arteries from killing him.

The next time I saw him, he looked like a ghost. Bent over with gray skin, he struggled with a walker to get to the bathroom every 20 minutes or so. From there the end of life came quickly – with a few difficult years that included cancer.

The ice cream manufacturers use combinations of flavors, and textures to make an ice cream experience so pleasurable you’ll want more and more.  Even the name of the flavor will make you laugh, helping you rationalize eating it. One study suggests that ice cream is addictive – like cocaine.

Frequent ice cream consumption is associated with reduced striatal response to receipt of an ice cream-based milkshake.

American Journal of Clinical Nutrition. 2012 Apr;95(4):810-7. Epub 2012 Feb 15.

Burger KS, Stice E.


Oregon Research Institute, Eugene, OR.



Weight gain leads to reduced reward-region responsivity to energy-dense food receipt, and consumption of an energy-dense diet compared with an isocaloric, low-energy-density diet leads to reduced dopamine receptors. Furthermore, phasic* dopamine signaling to palatable food receipt decreases after repeated intake of that food, which collectively suggests that frequent intake of an energy-dense food may reduce striatal response** to receipt of that food.

[* A phasic receptor is a sensory receptor that adapts rapidly to a stimulus.

** The dorsal striatum of the brain plays a role in food- consumption reward, and striatal dopamine receptors are known to be reduced in obese individuals.]


We tested the hypothesis that frequent ice cream consumption would be associated with reduced activation in reward-related brain regions (eg, striatum) in response to receipt of an ice cream-based milkshake and examined the influence of adipose tissue and the specificity of this relation.


Healthy-weight adolescents (n = 151) underwent fMRI during receipt of a milkshake and during receipt of a tasteless solution. Percentage body fat, reported food intake, and food craving and liking were assessed.


Milkshake receipt robustly activated the striatal regions, yet frequent ice cream consumption was associated with a reduced response to milkshake receipt in these reward-related brain regions. Percentage body fat, total energy intake, percentage of energy from fat and sugar, and intake of other energy-dense foods were not related to the neural response to milkshake receipt.


Our results provide novel evidence that frequent consumption of ice cream, independent of body fat, is related to a reduction in reward-region responsivity in humans, paralleling the tolerance observed in drug addiction. Data also imply that intake of a particular energy-dense food results in attenuated reward-region responsivity specifically to that food, which suggests that sensory aspects of eating and reward learning may drive the specificity.

PMID:2233803, NIH. NLM, PubMed access to Medline bibliographic citations

CR Way additions in [brackets]


Here’s what the tabloids say about it:

Study: Ice cream as addictive as cocaine

But ice cream addiction has a vulnerable underbelly. Unlike  some  addictive foods, like doughnuts or cookies, the protein in ice cream blocks serotonin production – the satisfaction neurotransmitter that helps you stop eating. So some ice cream addicts tend to eat more and more ice cream to feel satisfied.

A first step to breaking ice cream or other food addiction is to learn how to increase serotonin with healthful CR Way foods. When you do that, letting something like ice cream go is much easier. The extra serotonin will help you maintain your resolve to stick with your diet. In fact, many who travel the CR Way to Healthful Weight Loss report that they no longer feel the craving for comfort foods.

The April Healthful Weight Loss Getting Started teleconferences begin tomorrow night, Friday, April 20. That call focuses on increasing serotonin and other brain chemicals that help you feel satisfied and happy. Day Two, Saturday,  Sunday, April 21, shows you how to manage your foods with the NutriBase CR Way Edition Software, so you don’t have to guess about how to follow a CR Way diet. No accident — the Software includes serotonin-producing recipes.

Day Three, Sunday, April 22, focuses on glucose control with a special emphasis on weight loss and increasing another hormone that helps people break food addictions.

To see the details of the conferences, go to the Teleconference Schedule forum thread.

If you are a CR Way to Healthful Weight Loss member, send a note to from your e-mail address that’s associated with your membership, requesting the call-in details.

For more, see Making Healthful Foods Irresistible

Radioactive Drinking Water

This excellent in depth report from a local Texas television station is indicative of what is happening all  over the U.S. and in  many parts of the world. The good news is that an excellent distiller can remove  radioactive substances from drinking water.

We chose the Pure Water distiller because it is used by U.S. Embassies to protect the water supply from terrorist attacks with contaminants.

Find out more about Pure Water distillers







Mildly Elevated Glucose Impairs Cognition

This New York Times article reinforces the case for blood sugar control for improved cognition.

Blood Sugar Control Linked to Memory Decline, Study Says


Published: December 31, 2008

Spikes in blood sugar can take a toll on memory by affecting the dentate gyrus, an area of the brain within the hippocampus that helps form memories, a new study reports.

High glucose seemed to affect the dentate gyrus, part of the hippocampus

Researchers said the effects can be seen even when levels of blood sugar, or glucose, are only moderately elevated, a finding that may help explain normal age-related cognitive decline, since glucose regulation worsens with age.

 “If we conclude this is underlying normal age-related cognitive decline, then it affects all of us,” said lead investigator Dr. Scott Small, associate professor of neurology at Columbia University Medical Center. “The ability to regulate glucose starts deteriorating by the third or fourth decade of life,” he added.

“But the elevations in blood glucose seen in the new study are more subtle and would not be considered a disease state,” Dr. Small said.

“It’s part of the normal process of aging, much like wrinkling of skin,” he said. “It happens to all of us inexorably, and it worsens progressively across the life span.”

This article reports on the following research paper:

The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life.

Wu W, Brickman AM, Luchsinger J, Ferrazzano P, Pichiule P, Yoshita M, Brown T, DeCarli C, Barnes CA, Mayeux R, Vannucci SJ, Small SA.

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, NY, USA

Annals of Neurology. 2008 Dec;64(6):698-706.

A relevant excerpt from the full paper:

Showing that blood glucose selectively targets the dentate gyrus is not only our most conclusive finding, but it is the one most important for ‘normal’ aging—i.e., hippocampal dysfunction that occurs in the absence of disease states, such as AD, infarcts, and diabetes. Indeed, cognitive studies have established that normal age-related hippocampal dysfunction begins quite early, typically during the 4th decade of life, before the onset of age-related diseases. Furthermore, age-related hippocampal dysfunction occurs in all non-human mammals, who do not typically develop AD, stroke, or diabetes. Consistent with this, our cross-species findings document that the detrimental affects of glucose on the hippocampus occurs independent of AD and infarcts, and our monkey findings in particular suggest that it occurs independent of overt diabetes.

Beyond the obvious conclusion that preventing late-life disease would benefit the aging hippocampal formation, our findings suggest that maintaining glucose control, even in the absence of disease, should be strongly recommended to preserve cognitive health. More specifically, our findings predict that any intervention that causes a decrease in blood glucose should increase dentate gyrus function and would therefore be cognitively beneficial. In fact, separate studies examining the effects of physical exercise support this prediction. Imaging studies in humans and mice have documented that among all hippocampal subregions physical exercise causes a differential improvement in dentate gyrus function. By improving glucose metabolism, physical exercise also reduces blood glucose. It is possible, therefore, that the cognitive enhancing effects of physical exercise are mediated by the beneficial effect of lower glucose on the dentate gyrus. Whether through physical exercise or other behavioral or pharmacological interventions, our results suggest that improving glucose metabolism is a clinically tractable approach for ameliorating the cognitive slide that occurs in all of us as we age.

Read the full paper.

The researchers suggest exercise as a way of lowering glucose levels, but in our opinion exercise should not be the be all and end all for maintaining healthy glucose. Nor is high glucose an inevitable disease of aging. Great glucose control is being achieved by members of all ages. Users of the CR Way to Great Glucose Control rely on food selections, meal timing, and tease meals to jump start insulin production – examples of the many proven techniques to lower glucose.

The CR Way: Better than a weight-loss drug

If you are weight challenged, the temptation to a take a drug to lose weight increases. However, the U.S. FDA warns that weight-loss medications should not be taken unless you are at medical risk because of your weight. The reason is straightforward: too many side effects, some of them serious.


Drugs currently approved for weight loss

Table 1

Generic Name

Food and Drug Administration Approval for Weight Loss

Drug Type

Common Side Effects

Phentermine Yes; short term (up to 12 weeks) for adults Appetite Suppressant Increased blood pressure and heart rate, sleeplessness, nervousness
Diethylpropion Yes; short term (up to 12 weeks) for adults Appetite Suppressant Dizziness, headache, sleeplessness, nervousness
Phendimetrazine Yes; short term (up to 12 weeks) for adults Appetite Suppressant Sleeplessness, nervousness
Orlistat Yes; long term (up to 1 year) for adults and children age 12 and older Lipase Inhibitor Gastrointestinal issues (cramping, diarrhea, oily spotting), rare cases of severe liver injury reported
Bupropion No Depression Treatment Dry mouth, insomnia
Topiramate No Seizure Treatment Numbness of skin, change in taste
Zonisamide No Seizure Treatment Drowsiness, dry mouth, dizziness, headache, nausea
Metformin No Diabetes Treatment Weakness, dizziness, metallic taste, nausea


Notice that many of the drugs are not approved for long-term use, In three instances, the user is supposed to take them only for a maximum of 12 weeks – not long enough for most people to achieve significant weight loss benefits. And what do people do when they stop taking it? Unless they change their eating habits, they will gain the weight right back, possibly ending up heavier than before taking the drug.

The CR Way to Happy Dieting is far more effective than diet drugs. This happiness diet plan changes the biochemistry of the brain’s weight loss control center – helping decrease the desire to eat unhealthful comfort foods. Healthful Weight Loss Members, mark your calendar and make sure to join us Friday, March 30, for the first of three Healthful Weight Loss teleconferences. This one is the most important. Follow the advice and you will increase forever your enjoyment of food and ability to lose weight and then maintain it.

Software for managing optimal organ function

The opportunity for extending life grows brighter. While advances in the CR Way approach to caloric restriction and stem cell activation offer a whole-body approach to slowing aging, strategies to optimize the function of the body’s vital organs are also part of the CR Way approach.

For example, consider last night’s teleconference, which launched the CR Way Healthy Kidney Project. To slow and possibly reverse the age-related decline of kidney structure and its vital filtration function, we discussed how pure water and additional fluid intake can play an important role. Here, use of the NutriBase CR Way edition software to manage fluid intake is very helpful.

The soon-to-be-released NutriBase CR Way Software Edition 10 will add a new Kidney Stone Profile, which helps users evaluate the content of their fluids to make sure that oxalates and other dietary intake that may affect kidney function and plaque build-up are not excessive. It will also emphasize more advanced nutrient monitoring. Going beyond simple evaluations, along with vitamin and mineral intake, we will encourage users to be on the cutting edge by using the customized analysis, offered by the software’s “My Fields” function.

Consider this diagram that shows the approximate oxalate content of 100 grams of sweet potatoes, 29 mg. It’s an example of how you can use the flexible “My Fields” function to enter oxalate content of your favorite CR Way  foods.


Addition of the oxalate content allows analysis of one’s daily oxalate intake. Dietary oxalates are a prime risk factor for kidney stones, which occur among 2 million Americans every year and are increasing rapidly worldwide. See this:

Kidney Stones a Global Picture of incidence, prevalence and risk.

Romero V, Akpinar H, Assimos DG.
Reviws in Urology 2010 Spring;12(2-3):e86-96.
PMID:  20811557

Oxalates may also be involved in plaque accumulation:  Atherosclerotic Oxalosis in Coronary Arteries

“There are many forms of oxalosis, with deposition of oxalate crystals in various organs, including arteries. In this retrospective study we describe deposition of calcium oxalate crystals within atherosclerotic plaques in coronary arteries of four patients, a site of oxalate deposition not previously reported. We suggest the phrase “atherosclerotic oxalosis” for this finding.

Knowing the oxalate content of your diet is a first step in oxalate management. Citrate and fluid intake should also be monitored. The NutriBase CR Way Edition 10 will make oxalate management easier and ultimately improve kidney function and possibly preventing deadly oxalate build up in other tissues. And if you are at risk for painful kidney stones – you will have a new tool that helps you avoid them.

What if You Have Cancer?

If you have cancer, we will try our best to help you – working with you and your doctors to provide dietary and lifestyle approaches that have helped others fight the disease. We will need to know the type of cancer you have and any special risk factors that may have shown up in your blood tests.

We can then devise a special CR Way protocol that is customized for what is going on in your body.

Following a CR Way type of diet has been known for years to decrease cancer risk and slow metastasis. Other studies show that keeping glucose low may thwart some forms of cancer (See High Glucose Increases Cancer Risk)

Still others have found that lowering protein levels can affect cancer outcomes.

The CR way combines all of these dietary protocols as well as Daily Limited Fasting to give cancer patients the best chance to combat their disease.

Going beyond diet, the CR Way help you identify  holistic support so you have the best chance for healthful recovery.

Currently, the Web site has many resources that you can put to use immediately:

Cancer Page and sections in


Fighting Cancer

         Fasting Strategies

Countering Risk Factors

·  Excess Protein

·  High Glucose

·  PSA – Risk and Rate-of-Aging Indicator



            Cancer-fighting recipes

Foods to Choose

            High Anthocyanin, Flavanol, and Proanthocyanidin Content


Cancer blogs

Exercise, cancer, and p53

CaReFOR – a Breast Cancer Research project

Centenarians – Low cancer, slow cell division, long life

Wine – Cancer, Heart Disease, and Longevity Effects

Cancer Prevention Forums

Even as we write this, the field is changing, and we think our current research focus on microRNAs with Drs. Stephen Spindler and Joseph Dhahbi holds great promise for extending life – with practical application to combating cancer.

In addition to dietary interventions, eliminating any contaminants that might affect your body’s ability to fight cancer and/or are cancer-causing themselves is critically important.

Please see Carcinogens under cancer and the latest content on Pure Water both essential to reducing cancer risk.